Dermatologist Dr Dray on the safety of phenoxyethanol in skin care products. What is phenoxyethanol? Is phenoxyethanol safe in skin care and hair care? Should we avoid phenoxyethanol? #skincare #skincareingredients #skincarescience
0:16 What is phenoxyethanol
1:48 Reproductive harm?
2:06 Endocrine disruptor?
2:43 Neurologic problems?
6:25 Safety summary
7:10 Who should avoid phenoxyethanol?
7:49 Rant & ramble
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CIR (Cosmetic Ingredient Review). Final report on the safety assessment of phenoxyethanol. J Am Coll Toxicol 1990; 9: 259– 278.
Wang Q, Cui S, Zhou L et al. Effect of cosmetic chemical preservatives on resident flora isolated from healthy facial skin. J Cosmet Dermatol 2019; 18: 652– 658.
Beene KM, Scheman A, Severson D, Reeder MJ. Prevalence of preservatives across all product types in the contact allergen management program. Dermatitis 2017; 28: 81– 87.
Pastor‐Nieto MA, Alcántara‐Nicolás F, Melgar‐Molero V et al. Preservatives in personal hygiene and cosmetic products, topical medications, and household cleaners in Spain. Actas Dermosifiliogr 2017; 108: 758– 770.
EPA U. United States Environmental Protection Agency. Endocrine Disruptor Screening Program (EDSP) Estrogen Receptor Bioactivity, 2015. URL
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Garlantézec R, Warembourg C, Monfort C et al. Urinary glycol ether metabolites in women and time to pregnancy: the PELAGIE cohort. Environ Health Perspect 2013; 121: 1167– 1173.
Warembourg C, Binter A‐C, Giton F et al. Prenatal exposure to glycol ethers and sex steroid hormones at birth. Environ Int 2018; 113: 66– 73.
Warembourg C, Botton J, Lelong N et al. Prenatal exposure to glycol ethers and cryptorchidism and hypospadias: a nested case‐control study. Occup Environ Med 2018; 75: 59– 65.
Morton WE. Occupational phenoxyethanol neurotoxicity: a report of three cases. J Occup Med 1990; 32: 42– 45.
Béranger R, Garlantézec R, Le Maner‐Idrissi G et al. Prenatal exposure to glycol ethers and neurocognitive abilities in 6‐year‐old children: the PELAGIE Cohort Study. Environ Health Perspect 2017; 125: 684– 690.
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